Supplementary Figure S10 from Preclinical Activity of the B7-H3–Targeting Antibody–Drug Conjugate Vobramitamab Duocarmazine in Pediatric Solid Tumors
Year: 2026
Type: supplementary-materials
Abstract: Immunohistochemistry (IHC) staining of B7-H3. A, H-scores for B7-H3 protein in the cell membrane, cytoplasm, and vasculature of Wilms tumor, MRT, and hepatoblastoma models. B, Representative tumor samples showing the strongest (right column) and weakest (left column) B7-H3 protein expression in Wilms tumor (second row), MRT (third row), and hepatoblastoma (bottom row) panels. C, Example of H-scoring criteria.
Authors: Edward Favours, Haiying Tang, Peyton Wong, Samuel Ghilu, Vanessa del Pozo, Elena Mironova, Yidong Chen, Tim Stearns, Steven Neuhauser, Eric J. Earley, Stephen W. Erickson, Jee Young Kwon, Emily L. Jocoy, David Groff, Kateryna Krytska, Matthew Tsang, Beverly A. Teicher, Yael P. Mossé, E. Anders Kolb, Monirath Hav, Deryk Loo, Peter J. Houghton, Carol J. Bult, Richard G. Gorlick, John M. Maris, Malcolm A. Smith, Raushan T. Kurmasheva
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7169576166
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