Supplementary Figure S1 from CSF1R Inhibition with Chemotherapy Relieves Systemic Immune Suppression in Patients with Metastatic Triple-Negative Breast Cancer and Boosts Anti–PD-1 Efficacy in Transgenic Mammary Tumors
Year: 2026
Type: supplementary-materials
Abstract: Supplementary Figure S1 related to Figure 1 (A) CSF-1 levels in serum from phase 1b comparing C1D1, C1D2, and C2D1 at concentrations of PLX shown where each line reflects an individual patient, and colors indicate clinical response of 28 patients: No data on response (ND); progressive disease (PD); stable disease (SD); partial response (PR); deceased (DC).
Authors: Amanda Poissonnier, Hope S. Rugo, Wesley Horton, Tina Kim, Amy DeLuca, Eivind Valen Egeland, Tiziana Cotechini, Shamilene Sivagnanam, Motomi Mori, Yun Yu, Byung Park, Nicky Beelen, Dhaarini Murugan, Nell Kirchberger, Shivaani Kummar, Ingrid A. Mayer, Kimberly Blackwell, E. Shelley Hwang, Lisa M. Coussens
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7169596086