Work

Rectal Dieulafoy Lesion with Severe Hematochezia in a Warfarin-Treated Patient

Year: 2026

Type: article

Abstract: Dieulafoy lesions (DLs) are rare vascular malformations in the gastrointestinal tract that often present with gastrointestinal bleeding, most commonly in the stomach. Rectal DLs are exceptionally rare, representing less than 2% of cases. Warfarin use increases the risk for bleeding and management represents a challenge. We present a case of a 60-year-old male on chronic warfarin therapy who presented with severe hematochezia due to a rectal DL, requiring more than one colonoscopy and prothrombin complex concentrate (PCC) administration. While guidelines recommend PCC over fresh frozen plasma (FFP), they acknowledge that this is based on very low certainty of evidence.

Source: Journal of Community Hospital Internal Medicine Perspectives

DOI: 10.55729/2000-9666.1625

Authors: Carlos Elizondo Alatorre, Maria Gabriela Rubianes Guerrero, Julio C Valencia Manrique, Jennifer Harley

Institution: Metropolitan Hospital Center

Language: English

Topic: Gastrointestinal Bleeding Diagnosis and Treatment

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $500