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Mitochondrial-targeted nano-enhancer driving a self-amplifying NAD+ feedback loop to reprogram MSC spheroids metabolism for accelerated bone regeneration

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Year: 2026
Type: article
Source: Biomaterials
DOI: 10.1016/j.biomaterials.2026.124478
Authors: Hailong Li, Xifeng Liu, Wenkai Li, Areonna C. Schreiber, Sungjo Park, Abdelrahman M. Hamouda, Kaelyn L. Gasvoda, Andre Terzic, Benjamin D. Elder, Lichun Lu
Institutions: Mayo Clinic, Fudan University, Huashan Hospital
Language: English

Topic: Bone Tissue Engineering Materials
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Foundation for the National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases
Award: Injectable and Moldable Composite Bone Scaffolds for Spinal Fusion
OpenAlex ID: W7169858601
FWCI:
Cites: 46
Cited by:
Related to: 10
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