Work

Cancer-inspired, chimeric microparticles drive differential modulation of bone marrow-derived dendritic cells and potentiate diverse polarization in T cells

Year: 2026

Type: article

Abstract: Tregs compared to homopolymeric MP treatment, suggesting that combining TME-derived polymers into chimeric MPs may be synergetic for immunomodulatory function. The early studies on these novel cancer-inspired polymeric MPs demonstrate their potential as 'cargoless' inductors of diverse, immune regulatory responses and, their significant potential for applications in autoimmune and allergic disease therapy.

Source: Materials Advances

DOI: 10.1039/d6ma00884d

Authors: Gaddam Krishna, Allen B. Tu, Reuben Abraham, Zhenyu Wang, Dominic Clarke, Jamal S. Lewis

Institution: University of Florida

Language: English

Topic: Immunotherapy and Immune Responses

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,962