Work

Repeated Weight-Loss Dieting Reshapes Gut Microbiota and Regulates Gut–Hypothalamic Neuroendocrine Signaling

Year: 2026

Type: article

Abstract: Objectives: Weight cycling alters the gut microbiota, which may contribute to metabolic adaptation. However, its impact on hypothalamic pathways regulating hunger and satiety remains unclear. This study aimed to characterize weight-cycling-induced changes in the gut microbiota and evaluate their associations with hypothalamic neuroendocrine signaling.

Source: Current Developments in Nutrition

DOI: 10.1016/j.cdnut.2026.109082

Authors: Judy Kim, Rong Fan, Young-Cheul Kim, Yeonhwa Park, Soonkyu Chung

Institution: University of Massachusetts Amherst

Language: English

Topic: Gut microbiota and health

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,000