Serum Metabolomic Signatures of Regional Anthropometric Changes in Women With HIV after Switching to Integrase Strand Transfer Inhibitors
Year: 2026
Type: article
Study design: Observational Study
Abstract: Objectives: Women with HIV (WWH) often gain body weight after initiating integrase strand transfer inhibitor (INSTI)-based antiretroviral therapy (ART); we previously showed this weight gain is associated with inflammatory polyunsaturated fatty acid (PUFA) and oxylipin pathways. Here, we examined associations between changes in regional anthropometric measures and the serum metabolome in WWH receiving INSTIs.
Authors: Chin-An Yang, Young-Mi Go, Dean Jones, Bedi Chetna, Qian Yang, Christina Mehta, Igho Ofotokun, Anandi Sheth, Mohammed Ali, Sami Nadeem Teeny, Maria Luisa Alcaide, Frank Joseph Palella, Jordan Lake, Leah Rubin, Elizabeth Topper, Julie Schexnayder, Anjali Sharma, Julie Dumond, Jennifer Cocohoba, Seble Kassaye, Michael Augenbraun, Audrey French, Thomas Ziegler, Cecile Delille Lahiri, Jessica Alvarez
Institutions: Emory University, University of Miami, Northwestern University, The University of Texas Health Science Center at Houston, Johns Hopkins University, University of Alabama at Birmingham, Albert Einstein College of Medicine, University of North Carolina at Chapel Hill, University of California, San Francisco, Georgetown University, SUNY Downstate Health Sciences University, University of Illinois Chicago
Language: English
Subfield: Emergency Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $5,000
OpenAlex ID: W7170839348