Work

Choline Supplementation Reduces Metabolic Dysfunction-Associated Steatohepatitis (MASH) Severity in Offspring Exposed to Maternal Obesity

Year: 2026

Type: article

Abstract: Objectives: Maternal obesity and diabetes increase the risk for developing metabolic diseases in the offspring. Choline supplementation (CS) during maternal obesity has been shown to reduce excess adiposity and liver fat accumulation in the fetus. The study aimed to investigate whether CS in the prenatal and/or postnatal periods protected against Metabolic Dysfunction-Associated Steatohepatitis (MASH) pathogenesis induced by maternal obesity and a postnatal Western diet (WD) feeding.

Source: Current Developments in Nutrition

DOI: 10.1016/j.cdnut.2026.109350

Authors: Hrutvik Bhavsar, Hunter Korsmo, Steven Trasino, Jorge M Caviglia, Xinyin Jiang

Institutions: Brooklyn College, Hunter College

Language: English

Topic: Birth, Development, and Health

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,000