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A Randomized Dietary Trial in Newly Diagnosed Multiple Myeloma: The NUTRIVENTION-5 Protocol

Year: 2026
Type: article
Study design: Study Protocol
Abstract: Objectives: Despite patient interest, the effects of a dietary intervention for patients with newly diagnosed multiple myeloma (NDMM) outcomes is unknown. Building on our NUTRIVENTION trial (PMID: 413427390) that showed that a high-fiber plant-based (HFPBD) intervention improved quality of life (QOL), metabolic, microbiome and immune biomarkers, with delay in progression to NDMM in a subset, we hypothesize that patients with NDMM treated with standard quadruplet induction therapy who receive an HFPBD will have improved treatment response and QOL.
DOI: 10.1016/j.cdnut.2026.109277
Authors: Francesca Castro, Andriy Derkach, Sarah Rosenthal, Jeannen Santos, Jenna Blaslov, Sham Mailankody, Carlyn R Tan, Alexander M Lesokhin, Saad Z Usmani, Cynthia A Thomson, Urvi A Shah
Language: English
Subfield: Hematology
Field: Medicine
Open Access status: gold
Estimated APC paid: $5,000
OpenAlex ID: W7170905595
FWCI:
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