Work

Recurrent episodes of hypoglycemia as an initial presentation of pituitary stalk interruption syndrome: A case report

Year: 2026

Type: article

Abstract: Pituitary stalk interruption syndrome is a rare, congenital endocrine disorder of hypopituitarism. It has highly variable clinical presentation depending on the extent and type of hormonal deficiency and age at presentation, with growth hormone deficiency being the most common manifestation. Growth hormone plays an important role in maintaining normal blood glucose levels during stress or fasting, by stimulating hepatic gluconeogenesis and lipolysis. Therefore, hypoglycemia should alert us to a possibility of growth hormone deficiency necessitating imaging and facilitating early diagnosis of pituitary stalk interruption syndrome.

Source: Radiology Case Reports

DOI: 10.1016/j.radcr.2026.06.124

Authors: Radhika Thagunna, Shivali Rao, Binit Bajracharya, Jayaj Adhikari

Institution: Tribhuvan University Teaching Hospital

Language: English

Topic: Pituitary Gland Disorders and Treatments

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $600