Novel bi-heterocyclic-based Phosphine Ligands for Buchwald-type Amination of N-heterocyclic substrates
Year: 2026
Type: other
Abstract: Palladium-catalysed buchwald-type amination has been developed and employed for carbon-nitrogen bond formation for a long time. Coupling of N-heterocyclic substrates has been a challenging task due to the unwanted coordination of nitrogen’s lone pairs to Palladium, leading to the low catalytic overturn. Inspired by the successful catalytic performance of mono-heterocyclic-based Buchwald-type ligands in C-C bond formation reactions, a new series of bi-heterocyclic-based phosphine ligands were designed and synthesised, with multiple substrate scope demonstrated
Source: California Digital Library
DOI: 10.48321/d1c62e2552
Author: Chun pong Hui
Institution: Chinese University of Hong Kong
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
Funder: Chinese University of Hong Kong
OpenAlex ID: W7171297293
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