Year: 2026
Type: article
Abstract: A new bicyclic metabolite, rhodopyran ( 1 ), was isolated from the culture broth of Rhodococcus sp. strain RD066637. The planar structure was elucidated by 1D/2D NMR analyses and HRMS spectrometry, and the relative configuration was assigned from vicinal coupling constants and NOESY correlations, while the absolute configuration remains undetermined. Rhodopyran represents a structurally unusual carboxylated hexahydrocyclopenta[ b ]pyran and expands the known metabolite diversity of Rhodococcus , highlighting Rhodococcus as a source of uncommon natural-product scaffolds.
DOI: 10.3762/bjoc.22.89
Institution: Toyama Prefectural University
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7171504574