Targeting IRF5 with selective covalent oral small molecules attenuates Type I IFN and pro-inflammatory cytokine secretion in human PBMCs and in mice 2309520
Year: 2026
Type: article
Source: The Journal of Immunology
Authors: Shireen Khan, Sean Poust, Joselyn Del Cid, Zixiang Fang, David Lapointe, Suraj Ayer, Margot Paulick, Shashank Shrishrimal, Hanne Merritt, Weng In Leong, Kumar Hari, Jeremiah Heredia, Patrick Fitzgerald, Gabriela Colmenares, Irina Ankoudinova, Luke Monroe, Douglas Hansen, Stephen Hale, Lars Holten-Andersen, Robert Perni, Alun Bermingham, Jimmy Blair, Neil Dhawan, Sacha Holland, Tom Knudsen
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: closed
OpenAlex ID: W7171564224
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