Using the Neutrophil-lymphocyte Index in Predicting the Healing Time of Infected Trophic Ulcers in Patients With Chronic Venous Insufficiency
Year: 2026
Type: article
Study design: Observational Study
Abstract: The aim of this study is to evaluate the diagnostic value of the neutrophil-lymphocyte index (NLI) in determining the degree of infection of venous trophic ulcers (VTU) in patients with chronic venous insufficiency (CVI) of the lower extremities. NLI was found to be an optimal marker for diagnosing purulent-inflammatory diseases of soft tissues due to its ease of determination based on complete blood count data. Material and methods. The study is based on the observation of the neutrophil-lymphocyte index in 42 patients with VTU associated with chronic venous insufficiency (CVI) class C6 according to CEAP, who were inpatients in the surgical department of the Simferopol Central Regional Clinical Hospital from 2015 to 2020. The patients had VTU of various sizes and shapes in their lower extremities, with an area ranging from 6 to 12 cm2, and a duration of 4 weeks to 12 months. Patient observation lasted from 15 to 35 days during inpatient treatment. Results. The reduction in the NLI level in the control group was significantly less pronounced than in groups 2 and 3. In the control group, the NLI indicator decreased by only 9.7%, while in groups 2 and 3, this reduction was 51.15% and 53.97%, respectively. Conclusions. A direct correlation was observed between the reduction in the area of the VTU and the reduction in the neutrophil-lymphocyte index.
Institution: V.I. Vernadsky Crimean Federal University
Language: Russian
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7171687385