Work

Rational design of disordered proteins for sequence–function investigation

Year: 2026

Type: article

Source: Nature

DOI: 10.1038/s41586-026-10849-1

Authors: Kara Hunter, Trevor Brandt, Karina Guadalupe, Kavindu C. Kolamunna, Jeffrey M. Lotthammer, Nora M. Shamoon, Jessica K. Niblo, Brooke Nicholson, Lea M. Day, Alec Martinez, Alex S. Holehouse, Shahar Sukenik, Ryan J. Emenecker

Institutions: University of California, Merced, Syracuse University, Washington University in St. Louis

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Science Foundation, Alfred P. Sloan Foundation, Syracuse University, National Institutes of Health, University of California Merced, National Cancer Institute, Division of Biological Infrastructure, Core Research for Evolutional Science and Technology

Awards: BII: Life without water: protecting macromolecules, cells, and organisms during desiccation and rehydration across kingdoms of life, IntBIO: Collaborative Research: Functional Synergy Between Disordered Proteins and their Environment in Desiccation Protection, G3504179459, G385581388, G3972398431, CREST Center for Cellular and Biomolecular Machines, G5613623313, IntBIO: Collaborative Research: Functional Synergy Between Disordered Proteins and their Environment in Desiccation Protection, Uncovering the regulatory logic of gene expression encoded by disordered regions, G6479664167, G6671297155, Graduate Research Fellowship Program (GRFP), G7671779767, G7743023420, CAREER: Evolutionary Principles of Intrinsically Disordered Proteins, G9000022664, G9000116699

OpenAlex ID: W7171697397

FWCI: 3.656

Cites: 88

Cited by: 3

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