Work

Acute generalized exanthematous pustulosis following nemolizumab therapy in a patient with atopic dermatitis

Year: 2026

Type: article

Abstract: Acute generalized exanthematous pustulosis (AGEP) is a severe adverse reaction that demonstrates the rapid development of sterile, nonfollicular-based pustules on an erythematous base. Onset typically occurs within 24 to 48 hours of administration of the causative medication and presents with fever, rash, and leukocytosis.1 A wide range of medications have been reported to cause AGEP, with antibacterials being the most common.2 AGEP is a rare condition, with an estimated annual incidence of 1 to 5 million people worldwide.

Source: JAAD Case Reports

DOI: 10.1016/j.jdcr.2026.07.036

Authors: David Dunaway, Emma Madigan, Jina Chung, Liam Pettit, Ashely Aniyankunju

Institutions: University of New England, University of Pennsylvania

Language: English

Topic: Drug-Induced Adverse Reactions

Subfield: Pharmacology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $750