Isolated Primary B-Cell Lymphoma of the Larynx Mimicking Carcinoma: 18F-FDG PET/CT Findings
Year: 2026
Type: article
Study design: Case Report
Abstract: Primary laryngeal lymphoma is an extremely rare extranodal manifestation of non-Hodgkin lymphoma, accounting for less than 1% of all laryngeal neoplasms. We report a case of isolated primary B-cell lymphoma of the larynx evaluated with 18F-FDG PET/CT imaging. PET/CT demonstrated intense FDG uptake (SUVmax: 16.3) in the laryngeal lesion, while mild FDG uptake (SUVmax: 5.5) was observed in the right palatine tonsil, likely of inflammatory origin. The patient underwent R-CHOP therapy, and both interim and post-treatment PET/CT scans showed complete metabolic and anatomic response. This case highlights the critical role of 18F-FDG PET/CT in the staging and management of rare primary laryngeal lymphomas.
Source: Molecular Oncologic Imaging
DOI: 10.71286/moi.1928922
Authors: Zehranur Tosunoğlu, Ömer Faruk Şahin
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7171815800