Work

Seven days of warm water immersion modulate baseline fluid-regulatory hormones without altering acute multisystem physiological stress responses in older males

Year: 2026

Type: article

Abstract: This study demonstrates that short-term (7 days) passive heat acclimation via warm water immersion induces selective endocrine adaptation without uniform protection across physiological systems in older males aged 60-80. Although RAAS-mediated fluid regulation was modified following heat acclimation, gastrointestinal and renal stress responses to acute heat exposure persisted. These findings suggest that physiological adaptation to repeated heat exposure in aging may be compartmentalized across organ systems, with implications for vulnerability during extreme heat events.

Source: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

DOI: 10.1152/ajpregu.00099.2026

Authors: Ben J. Lee, James J. McCormick, Kelli E. McCormick, Kristina-Marie T. Janetos, Glen P. Kenny

Institutions: Hartpury University, University of Ottawa, Ottawa Hospital Research Institute

Language: English

Topic: Thermoregulation and physiological responses

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Natural Sciences and Engineering Research Council of Canada