Prioritizing shared neoantigens profiling across analytical platforms for an inclusive cancer immunotherapy: from bench to the point-of-care frontier
Year: 2026
Type: article
Abstract: Shared neoantigens and cancer-related biomarkers are suitable biomolecules with the potential to pursue equitable cancer early diagnosis and immunotherapy at large scale. This review outlines the current repertoire on shared neoantigens and critically assesses the landscape of analytical platforms for their profiling, with a focus on their translation from laboratory-scale systems to emerging single-molecule detection technologies, paving the way toward point-of-care testing as the ultimate ultrasensitive analytical strategy with significant scalability.
Source: npj Biosensing
Authors: Erika Castrignanò, Eleonora Macchia, Valentina Morciano, Paolo Bollella, Alessandra Costantino, Valentina Mongelli, Lucia Sarcina, Ilaria Iacobellis, Mariapia Caputo, Francesco Leonetti, Luisa Torsi
Institutions: University of Bari Aldo Moro, Åbo Akademi University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $2,590
Funders: Ministero della Salute, Regione Puglia
OpenAlex ID: W7171842355
