Work

Stereoselective Synthesis of β‐ C ‐glycosides From Exoglycals Through Radical C─C Bond Formation

Year: 2026

Type: article

Abstract: We describe herein a convenient strategy for the preparation of β-C-glycosides via the addition of radical species onto exoglycals. This method is efficient, general and achieved in mild conditions starting from xanthates derivatives and using triethylborane as initiator and 4-tert-butylcatechol as hydrogen atom source. This hydroalkylation reaction is completely regioselective with moderate to complete stereoselectivity.

Source: Chemistry - A European Journal

DOI: 10.1002/chem.71515

Authors: Noémie Murard, Guillaume Pilet, David Gueyrard

Institutions: Lyon 1 Université, Centre National de la Recherche Scientifique, Institut de Chimie et Biochimie Moléculaires et Supramoléculaires, Laboratoire des Multimatériaux et Interfaces

Language: English

Topic: Carbohydrate Chemistry and Synthesis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,640

Funders: Université Claude Bernard Lyon 1, Conseil National de la Recherche Scientifique