Work

Segmental Pallor and Hair Loss in a Patient With Ross Syndrome: Case Report

Year: 2026

Type: article

Abstract: A 30-year-old male sought medical consultation due to sudden anisocoria. Clinical examination confirmed Adie's tonic pupil. Subsequently, the presence of segmental anhidrosis with compensatory hyperhidrosis and areflexia established the diagnosis of Ross syndrome. In a 15-year follow-up, uncommon manifestations developed in the facial territory affected by compensatory hyperhidrosis: unilateral facial pallor and alopecia following a midline-defined pattern. This case emphasizes the importance of recognizing neurocutaneous manifestations in dermatology practice and suggests that Ross syndrome may encompass a broader spectrum of dermatological findings than currently recognized.

Source: The Journal of Dermatology

DOI: 10.1111/1346-8138.70444

Authors: Markus Augusto Martínez Holst, Ana María Sierra Valiente, Francisco Alejandro Silva Navarro, Paola Picazo León, Carolina De La Paz Cruz, Frida Aguilera Villa

Institutions: Universidad Anáhuac, UNSW Sydney

Language: English

Topic: Sympathectomy and Hyperhidrosis Treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,630