Work

An ER stress-responsive RNA rheostat for programmable gene and mRNA therapies

Year: 2026

Type: article

Source: Cell chemical biology

DOI: 10.1016/j.chembiol.2026.07.006

Authors: Roza Ogurlu, Eliya B. Sanchez, Joshua A. Hull, Sophia M. Fergione, Vivian Yudistyra, Gabriela M. Webb, Helen L. Wu, Cleiton T. Pessoa, Matthew C. Humkey, Sofia K. Potter, Alan Rosales, Heather A. Vincent, Jonah B. Sacha, Aravind Asokan

Institutions: Duke University, Duke Medical Center, Oregon National Primate Research Center, Oregon Health & Science University, Vaccine and Gene Therapy Institute

Language: English

Topic: Endoplasmic Reticulum Stress and Disease

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: Dissecting AAV silencing in humanized mice, Determinants of AAV Tropism, ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale Modeling, Evolving Novel AAV Vectors for Gene Therapy to Cure HIV

OpenAlex ID: W7172490504

FWCI:

Cites: 54

Cited by:

Related to: 10