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Optimizing CRISPR/Cas9 genome editing in primary human hematopoietic cells to advance studies into HIV biology

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Year: 2026
Type: preprint
Source: bioRxiv (Cold Spring Harbor Laboratory)
DOI: 10.64898/2026.08.05.741689
Authors: Hong-Ru Chen, Nicole P. Kadzioch, Madeleine Gapp, Hsiu-Hui Yang, Adrian Ruhle, Javier Villamizar Cujar, Thimo Fuchs, Niklas A. Schmacke, Veit Hornung, Roberto F. Speck, Oliver T. Keppler, Manuel Albanese
Institutions: Max-von-Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Ludwig-Maximilians-Universität München, University of Zurich, University Hospital Zurich, German Center for Infection Research, University of Milan, Istituto Nazionale Genetica Molecolare
Language: English

Topic: CRISPR and Genetic Engineering
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funder: Deutsche Forschungsgemeinschaft
Award: G6856850593
OpenAlex ID: W7172496274
Cites: 69
Cited by:
Related to: 10
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