Work

Multicomplex Integrative Structural Modeling of a Human Histone Deacetylase Interactome

Year: 2026

Type: article

Abstract: Here, we present a complete integrative structural model of a NuRD subcomplex including the abundant HDAC1:MBD3:MTA1:GATAD2B:RBBP4 subunits. This new version provides a complex formed by these individual proteins (HDAC1, MBD3, MTA1, and RBBP4).

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.21811899

Authors: Nde, Jules, Majila, Kartik, Zimmermann C., Rosalyn, Kempf, Cassandra, Zhang, Ying, Cesare, Joseph, Thornton L., Janet, Workman L., Jerry, Florens, Laurence, Viswanath, Shruthi, Washburn P., Michael

Institutions: The University of Kansas Cancer Center, National Centre for Biological Sciences, Stowers Institute for Medical Research, Washington University in St. Louis

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W7172500577

FWCI:

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