Year: 2026
Type: article
Abstract: The direct conversion of alkenes to 1,2-diols is typically achieved via epoxidation followed by hydrolysis or by metalcatalyzed dihydroxylation, often requiring stoichiometric additives and generating undesired byproducts.Hydrogen peroxide is an attractive green oxidant; however, its implementation in continuous flow remains challenging due to the conflicting requirements of the epoxidation and hydration steps.Kon, Kobayashi, and co-workers from the National Institute of Advanced Industrial Science and Technology in Japan developed an acid-free continuous-flow process using titanium silicalite-1 (TS-1) as a heterogeneous catalyst, enabling tandem epoxidation and hydration with aqueous H 2 O 2 (Adv.Synth.Catal.,
Language: English
Open Access status: bronze
OpenAlex ID: W7196934753