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Varhaiselämän stressin yhteys mentalisaatioon ja siihen liittyvään aivoaktivaatioon nuorilla aikuisilla

Year: 2026
Type: article
Study design: Observational Study
Abstract: Aims: The association between early-life stress (ELS) and later socio-cognitive development has been widely studied, but associations between ELS and mentalization remain less well understood. This study examined whether ELS was associated with mentalization, which was measured with the Reading the Mind in the Eyes Test (RMET). The task was performed during functional magnetic resonance imaging (fMRI), which enabled the examination of task-related brain activation. Methods: The sample consisted of 89 young adults who were part of the Tampere University Miracles of Development longitudinal study, in which families have been followed from pregnancy to early adulthood. Questionnaire data related to ELS had been collected from the families during pregnancy and during the child’s first year of life, and these data were used to form an ELS sum variable. Mentalization was assessed as accuracy in the RMET task performed during fMRI. In the behavioral analyses, a linear regression model was used to examine the association between ELS and RMET task accuracy. Brain activity was examined as task-related BOLD activation in a priori defined brain regions, which were mPFC, ACC, IFG, TPJ, and pSTS. Brain activation was analyzed using separate regression models in both hemispheres of the regions. Conclusions: The results did not show a clear association between ELS and RMET task accuracy or between ELS and task-related brain activation within the selected regions. These findings suggest that, in this sample, ELS was not clearly associated with mentalization at the behavioral level or with task-related activation in the selected brain regions.
Language: English
Field: Psychology
Open Access status: green
OpenAlex ID: W7198658305
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