Machine learning surrogate forward models for biomechanical laryngeal control
Year: 2026
Type: article
Abstract: Accurate modeling of laryngeal motor control is key to understanding typical and disordered voice production. However, traditional biomechanical plant models based on ordinary differential equations (ODEs) often involve high computational costs and numerical instabilities, limiting their use in real-time closed-loop control frameworks. This study evaluates feature-driven machine learning (ML) regressors, specifically Random Forest (RF), Multilayer Perceptron Neural Networks (NN), and Polynomial Regression (PR), as surrogate forward models mapping laryngeal motor inputs to fundamental frequency and sound pressure level. Training data were generated with two biomechanical vocal fold models: the extended body-cover and the triangular body-cover. Results demonstrate that ML surrogates reduce execution times from seconds to milliseconds (e.g., 2 ms for PR), enabling stable real-time tracking via inverse Jacobian control. While RF provides the highest accuracy, NN and PR offer smoother control signals and smaller memory footprints. A practical performance threshold was identified near N = 1,000 training samples, below which accuracy degraded substantially when models were trained from scratch. These findings support ML surrogates as efficient and adaptable alternatives to direct numerical simulation, providing a foundation for future subject-specific modeling through transfer learning in data-limited clinical scenarios.
DOI: 10.1121/10.0044564
Language: English
Topic: Voice and Speech Disorders
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: SUBJECT-SPECIFIC REPRESENTATIONS OF LARYNGEAL MOTOR CONTROL USING LOW-ORDER MODELS OF VOICE PRODUCTION, G1547686101, G2084978379, G2669363854, G2982694393, G371350066, G5302412505, DOMAIN ADAPTATION OF SUBJECT-SPECIFIC MODELING FOR AMBULATORY ASSESSMENT OF LARYNGEAL BIOMECHANICAL COMPONENTS., G8383608706, G9000003783, G9000278013
OpenAlex ID: W7201878603
