P2-seq resolves topology-dependent DNA structural states and their long-range coupling in individual molecules
Year: 2026
Type: dataset
Abstract: This dataset contains raw Oxford Nanopore PromethION signal data from the high-salt plasmid experiments performed as part of the P2-seq study. Raw nanopore signal data are stored in POD5 format and provided as one compressed TAR.GZ archive per sample. The corresponding basecalled and aligned sequencing reads are deposited separately in the NCBI Sequence Read Archive under BioProject PRJNA1504906. The files correspond to the following NCBI BioSamples: high_salt_control.tar.gz — SAMN62191347 — pFLIP-FUSE linearized untreated control high_salt_s1.tar.gz — SAMN62191348 — high-salt topoisomer population, supercoiling level 1, KMnO4-treated high_salt_s2.tar.gz — SAMN62191349 — high-salt topoisomer population, supercoiling level 2, KMnO4-treated high_salt_s3.tar.gz — SAMN62191350 — high-salt topoisomer population, supercoiling level 3, KMnO4-treated high_salt_s4.tar.gz — SAMN62191351 — high-salt topoisomer population, supercoiling level 4, KMnO4-treated high_salt_s5.tar.gz — SAMN62191352 — high-salt topoisomer population, supercoiling level 5, KMnO4-treated high_salt_s6.tar.gz — SAMN62191353 — high-salt topoisomer population, supercoiling level 6, KMnO4-treated high_salt_s7.tar.gz — SAMN62191354 — high-salt topoisomer population, supercoiling level 7, KMnO4-treated high_salt_s8.tar.gz — SAMN62191355 — high-salt topoisomer population, supercoiling level 8, KMnO4-treated Each TAR.GZ archive contains the POD5 file corresponding to the sample with the same basename.
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7202030272
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