Work

Mega-enhancers compartmentalize transcriptionally active long genes in the brain

Year: 2026

Type: article

Source: Nature Cell Biology

DOI: 10.1038/s41556-026-02043-2

Authors: Ziyu Zhao, Omar A. Payán Parra, Shin-ichiro Fujita, Francesco Musella, Nicolas J. Scrutton Alvarado, Frank Alber, Yue Yang, Tomoko Yamada

Institutions: Northwestern University, University of California, Los Angeles

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Science Foundation, Northwestern University, National Institutes of Health, National Institute on Drug Abuse, National Human Genome Research Institute, National Institute of Neurological Disorders and Stroke, Common Fund

Awards: Mechanisms of Genome Organization in Brain Development and Behavior, G2587344121, G2994998762, NSF-Simons National Institute for Theory and Mathematics in Biology, G4570068243, Multiscale Analyses of 4D Nucleome Structure and Function by Comprehensive Multimodal Data Integration, Mechanisms of Genome Architecture Regulation in Motor Learning

OpenAlex ID: W7202074996

FWCI:

Cites: 123

Cited by: 7

Related to: 10