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Germline BRCA1 Mutation Deregulates Irradiation–Induced Cell Cycle Checkpoints in Human Mammary Luminal Progenitors

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Year: 2026
Type: preprint
Source: bioRxiv (Cold Spring Harbor Laboratory)
DOI: 10.64898/2026.08.11.743512
Authors: Abhijith Kuttanamkuzhi, Bowen Zhang, Kelvin Yeung, Matthew Waas, Pirashaanthy Tharmapalan, Soumili Sarkar, Curtis W. McCloskey, Olivia Drummond Guy, Hui Fang, Shreya Mishra, Thomas Kislinger, Hal K. Berman, Shane M. Harding, Rama Khokha
Institutions: University Health Network, Princess Margaret Cancer Centre, University of Toronto, University of Pittsburgh
Language: English

Topic: BRCA gene mutations in cancer
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Breast Cancer Society of Canada, Canadian Institutes of Health Research, Canadian Cancer Society Research Institute
OpenAlex ID: W7202252208
Cites: 60
Cited by:
Related to: 10
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