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Diffuse Leptomeningeal Glioneuronal Tumor With Peritoneal Seeding After Ventriculoperitoneal Shunt in an Adult Patient: A Case Report

Year: 2026

Type: article

Abstract: mutations with 1p deletion. The patient received craniospinal irradiation followed by temozolomide chemotherapy, achieving temporary disease stabilization. Fifteen months after diagnosis, she developed massive ascites, and peritoneal biopsy confirmed metastatic dissemination consistent with DLGNT. Despite treatment, she died 18 months after initial diagnosis. This case highlights the diagnostic challenge of adult DLGNT, the molecular heterogeneity of the disease, and the potential risk of peritoneal dissemination following VP shunt placement. Awareness of possible extraneural spread is essential in managing this rare tumor.

Source: Brain Tumor Research and Treatment

DOI: 10.14791/btrt.2026.0010

Authors: Chaejin Lee, Ki-Su Park, Seong-Hyun Park, Mee-seon Kim, Jeong-Hyun Hwang

Institution: Kyungpook National University

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7202349980

FWCI:

Cites: 19

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Related to: 10