DART-MLCI: A design-aware microfluidic chip paradigm for real-time live-cell image analysis
Year: 2026
Type: software
Abstract: DART-MLCI performs real-time microfluidic region-of-interest (RoI) image processing: it takes a raw microscopy frame, detects alignment markers, rotates and crops the RoI, masks the region of interest, and segments cells automatically for any chip design described by a single JSON config (fine alignment). It further provides time-constant microfluidic chip mapping: several RoI positions on the microfluidic chip are recorded while it is on the microscope stage, and the microfluidic blueprint is aligned to stage coordinates, yielding all RoI positions for any chip design described by a single JSON config (coarse alignment).
Institutions: Forschungszentrum Jülich, RWTH Aachen University
Language: English
Subfield: Biophysics
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7203498236
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