Work

Concentrations, Distribution, Sources, and Risks of Pharmaceutical and Personal Care Products in the Karst Landscape of the Lijiang River Basin

Year: 2026

Type: article

Abstract: Owing to their widespread occurrence, pharmaceutical and personal care products (PPCPs) have emerged as a global environmental concern; however, research on PPCP pollution in karst tourist cities remains limited. This study investigated the concentrations and spatial distribution of 43 PPCPs in the Lijiang River Basin and identified their primary sources together with the associated ecological and health risks. In total, 43 target PPCPs were detected in the Lijiang River Basin in Guangxi, China, with concentrations ranging from 68.6 to 3170 ng/L in wastewater, 53.2 to 1400 ng/L in surface water, and 32.0 to 505 ng/L in groundwater. Caffeine (CAF), 1,7-dimethylxanthine (1,7-DIM), 4-acetaminophenol (APAP), and metformin (MFM) were the predominant contaminants across all three matrices. Notably, concentrations in tributaries exceeded those in the main stem. Principal component analysis (PCA) revealed that domestic sewage and hospital wastewater constitute the principal sources of PPCPs in the Lijiang River. Certain effluents and river reaches containing 1,7-DIM and MFM posed a moderate ecological risk (0.1 < risk quotient (RQ) < 1). The PPCPs detected in groundwater did not exceed health-based thresholds, indicating no direct risk to human health. These findings advance our understanding of PPCP contamination in karst landscapes and provide a scientific basis for water quality management in the Lijiang River Basin.

Source: Environments

DOI: 10.3390/environments13080455