Article 6. Theory of Memory: the Origin of the Genetic Apparatus
Year: 2026
Type: preprint
Abstract: According to the Non-Information Theory of Life (NJT), life is defined as the ability of a supramolecular ensemble to maintain its identity in a continuous exchange of matter and energy. In previous work, we have shown how water in ordered tetraphases (S, γ, δ) creates tetrasignatures — energy reliefs that guide the polymerization of monomers, and how carbomorphosis fixes these imprints in stable carbosignatures. Now we pose the question: how did these precellular structures give rise to polymer heredity, cellular memory, and the nucleus? This paper proposes a physical scenario for the transition from supramolecular ensembles (SMAs) to RNA, DNA, and the cell nucleus. It has been shown that S-tetraphase provides the synthesis of short oligomers (3–10 monomers), γ-tetraphase provides the synthesis of long RNAs (30–50 monomers) and the occurrence of replication through a conformational matrix, and δ-tetraphase provides chiral selection and homochirality. Tetrassignatures in the nucleomorphic γ-tetraphase direct the synthesis of RNA and then DNA, which becomes a chemically stable archive of aqueous fingerprints. The nucleus arises as a physical necessity — the isolation of slow nucleomorphic water from fast cytomorphic water. Epigenetic tags are interpreted as carbosignatures fixed on chromatin and directed by tetrasigsignatures in the nucleomorphic tetraphase. The work combines the theory of tetrasignatures with modern data on biomolecular condensates (LLPS), prebiotic nucleotide synthesis and the origin of eukaryotes, offering a continuous physical pathway from precellular structures to the genetic machinery.
Author: Лагода, Владимир
Language: English
Subfield: Astronomy and Astrophysics
Field: Physics and Astronomy
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W7203635092
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