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A Scalable and Safe Synthesis of Ramelteon: Integrating Batch Steps with Asymmetric Hydrogenation and Microreactor Technology

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Year: 2026
Type: article
Source: Organic Process Research & Development
DOI: 10.1021/acs.oprd.5c00521
Authors: Renbing Wang, Wenjie Yu, Chen Yang, Kaiyu Gao, Jiale Hu, Rui Zhang, Junyin Liu, Ruitong Zhao, Lexi Niao, Chengyang Li, Liuxiang Zhu, Zhiyu Li, Xi Xu, Zhisheng Zhang, Jubo Wang
Institution: China Pharmaceutical University
Language: English

Topic: Asymmetric Hydrogenation and Catalysis
Subfield: Inorganic Chemistry
Field: Chemistry
Domain: Physical Sciences

Open Access status: closed

Funders: National Natural Science Foundation of China, Government of Jiangsu Province, Natural Science Foundation of Jiangsu Province, Fundamental Research Funds for the Central Universities
Awards: G1286481864, G212837511, G2418631491, G2437836368, G3813908907, G6672251988, G6995860541, G7677495655, G8715177295
OpenAlex ID: W7203635200
FWCI:
Cites: 18
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