Work

Drug-Eluting Bioabsorbable Stents in Rhinology: A Decadal Meta-Analysis

Year: 2026

Type: article

Study designs: Systematic Review, Meta-Analysis

Abstract: Steroid-eluting nasal implants and stents are designed to maintain sinus patency after endoscopic sinus surgery (ESS) while delivering corticosteroids locally to reduce inflammation and polyp recurrence. This meta-analysis integrates in vitro data, observational studies, and randomized controlled trials (RCTs) assessing absorbable, steroid-eluting devices in sinonasal surgery. Safety, efficacy, and the outcomes reported by patients were the primary factors examined. All relevant literature was included thanks to a PRISMA-guided approach. A steroid-eluting device reduces the need for revision surgery and the recurrence of polyps in some patients while consistently improving early postoperative outcomes, including pain, mucosal edema, and synechiae formation. Real-world data indicates that fewer people are using healthcare services. Comparing studies is challenging due to the variety of devices and endpoints. Steroid-eluting implants can help control inflammation and, in certain cases, greatly speed up recovery after ESS. More multicenter randomized controlled trials (RCTs) with standardized outcomes and longer follow-up are necessary to improve their clinical application.

Source: Indian Journal of Otolaryngology and Head & Neck Surgery

DOI: 10.1007/s12070-026-06809-w

Authors: T. M. Amulya, C. C. Deepu, Gouhar Sha

Institutions: JSS Medical College and Hospital, JSS Academy of Higher Education and Research

Language: English

Topic: Sinusitis and nasal conditions

Subfield: Otorhinolaryngology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,290