Work

From mitochondria to arrhythmia: Rare phenotype of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes presenting with long QT type 3 pattern

Year: 2026

Type: article

Abstract: Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like episodes (MELAS) is a rare, mitochondrial-inherited, multisystem disorder often presenting early in life with unexplained headaches, seizures, myopathy, neurologic deficits, early onset diabetes, and profound lactic acidosis1. The diverse clinical manifestations of mitochondrial disease reflect the role of mitochondria in cellular energy production and their ubiquitous presence throughout the body.

Source: HeartRhythm Case Reports

DOI: 10.1016/j.hrcr.2026.07.033

Authors: Kevin Benavente, Yu-Chiang Wang, Sarah Abdul Ghani, Abdulelah Nuqali, Helaine Kwong

Institutions: University of Hawaiʻi at Mānoa, University of Hawaii System

Language: English

Topic: Mitochondrial Function and Pathology

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,100