Work

Discovery of Monoterpenoid Indole Alkaloids Targeting CCN1 to Suppress Autophagy for the Treatment of Hypoxic Kidney Injury

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6c02215

Authors: Xue Qiao, Shun-Qing Chen, Ariel M. Sarotti, Jixian Zhang, Yu-Ting Zhong, Wei-Chen Chen, Xiaofen Wang, Wumei Wang, Jianying Huang, Xiao-Yan Wu, Hui-Ming Wang, Shugeng Cao, Zhengqiu Li, Qihao Wu, Yuling Xiao, Xuechuan Hong, You-Sheng Cai

Institutions: Chinese Academy of Sciences, Wuhan University, National University of Rosario, Jinan University, Tibet University, University of Hawaii at Hilo, University of Pittsburgh, Fudan University

Language: English

Topic: Alkaloids: synthesis and pharmacology

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Bill and Melinda Gates Foundation, National Natural Science Foundation of China, Natural Science Foundation of Shandong Province, Science, Technology and Innovation Commission of Shenzhen Municipality, Zhongnan Hospital of Wuhan University, National Key Research and Development Program of China, Fundamental Research Funds for the Central Universities, Science and Technology Plan Projects of Tibet Autonomous Region

Awards: G1766953473, G3692359973, G4550366031, G4846912483, G5540430892, G5927573182, G6135496089, G6246428548, G6683186570, G6730241693, G8001225018, G8013616988, G8140632254, G8152383357, G8909815416, G8938187555

OpenAlex ID: W7203705406

FWCI:

Cites: 54

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