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The live attenuated DGAT1 -knockout whole-cell Toxoplasma vaccine confers protective immunity against acute and chronic toxoplasmosis

Year: 2026

Type: preprint

Source: Research Square

DOI: 10.21203/rs.3.rs-10755545/v1

Authors: Isabelle Coppens, Shahbaz Khan, Yevel Flores-Garcia, Jiro Sakai, Mustafa Akkoyunlu, Julia Romano, Karen Ehrenman, Viviana Pszenny, Michael Grigg, Krishna Manuguri, Yue Zhao, Duanpei Wang, Fidel Zavala

Institutions: Johns Hopkins University, United States Food and Drug Administration, National Institutes of Health, National Institute of Allergy and Infectious Diseases

Language: English

Topic: Toxoplasma gondii Research Studies

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, Fisher Center for Alzheimer's Research Foundation, Johns Hopkins University, National Institutes of Health, Johns Hopkins Bloomberg School of Public Health, National Institute of Allergy and Infectious Diseases

Awards: G528506492, G861641175

OpenAlex ID: W7203721846

Cites: 65

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