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Small-molecule activation of the tumor suppressor kinase LKB1 via the pseudokinase STRAD

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Year: 2026
Type: article
Source: Cell chemical biology
DOI: 10.1016/j.chembiol.2026.07.013
Authors: Lin Song Kretschmer, Dominique C. Mitchell, Jin Liu, Logan Leak, Rigney E. Turnham, LeeAnn Wang, Zheng Wang, Changliang He, Luo Ding, Marc Adler, Timothy Kellett, Aidan Keith, Yeonjoo C. Hwang, Gary K.L. Chan, Robert L.G. Gottschalk, Weicheng Li, Lieza M. Chan, Roopa Ramamoorthi, Sarah Lively, Robert A. Drakas, Vijay Ramani, Tingting Qing, Kliment A. Verba, Trever Bivona, Jonathan M.L. Ostrem, Richard T. Beresis, John D. Gordan
Institutions: University of California, San Francisco, UCSF Helen Diller Family Comprehensive Cancer Center
Language: English

Topic: Protein Kinase Regulation and GTPase Signaling
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W7203724129
FWCI: 1.939
Cites: 64
Cited by: 1
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