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AMITO: an open-access application for assisted analysis of mitochondria in transmission electron microscopy images

Year: 2026

Type: article

Abstract: AMITO is an open-access, standalone application for mitochondrial analysis from TEM images that combines automated and manual workflows within a single user-friendly interface. Validated against conventional FIJI analysis, AMITO demonstrated excellent reproducibility while substantially reducing analysis time and experimenter-dependent variability. By integrating morphology and ultrastructure quantification without requiring programming expertise, AMITO provides a reliable and accessible solution to improve robustness, efficiency, and reproducibility in mitochondrial research.

Source: American Journal of Physiology-Cell Physiology

DOI: 10.1152/ajpcell.00300.2026

Authors: Elyse Hucteau, Thomas J. Hureau, Allan F. Pagano, Joris Mallard

Institutions: Institut Strauss, Université de Strasbourg

Language: English

Topic: Cell Image Analysis Techniques

Subfield: Biophysics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

OpenAlex ID: W7203724401

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Cites: 26

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