Optimal timing for hepatic cyst intervention: Predictive factors for complete resolution after ethanol sclerotherapy
Year: 2026
Type: article
Study design: Observational Study
Abstract: Background and Objectives: The optimal timing of ethanol sclerotherapy and predictors of complete resolution (CR) in patients with symptomatic hepatic cysts remain unclear. This study aimed to identify clinical and procedural predictors of CR and to determine a volume-based threshold that may guide patient selection. Methods: We retrospectively analyzed 307 patients who underwent percutaneous catheter drainage-guided or EUS-guided ethanol sclerotherapy between 2003 and 2023. CR was defined as <5% of baseline cyst volume. Receiver operating characteristic analysis identified a volume threshold for CR, and multivariable logistic regression was used to determine independent predictors. Results: = 0.678). Conclusion: Initial hepatic cyst volume is an important factor influencing treatment outcome. The 233 mL threshold may inform the timing of intervention alongside symptoms and patient-specific factors.
Source: Endoscopic Ultrasound
Institutions: Asan Medical Center, University of Ulsan, Chulalongkorn University
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7203726527