Work

Tumor-derived PTX3 drives an immunosuppressive myeloid landscape and inhibits CD8 T cell-mediated anti-tumor immunity via PI3K-dependent signaling

Year: 2026

Type: article

Source: Oncogene

DOI: 10.1038/s41388-026-03936-0

Authors: Mohamed Y. Zaky, Monika Vashisht, Mohammad A. I. Al-Hatamleh, Karen Siddoway, Jennifer Yan, Anthony Bragoli, Jessy John, Huaibin Ge, Zhangguo Chen, Jing H. Wang

Institutions: University of Pittsburgh, UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, UPMC Health System

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute

Awards: Cancer Immunology Training Program, Head and Neck Cancer SPORE

OpenAlex ID: W7203753981

FWCI:

Cites: 53

Cited by:

Related to: 10