Decoding dietary pectin: from structural complexity and microbial CAZyme–PUL networks to cross-feeding and host-beneficial metabolites
Year: 2026
Type: article
Abstract: , utilize these breakdown products via specialized transport systems. Intracellular fermentation leads to the synthesis of a series of degradation products, such as acetate, propionate, and butyrate, which are crucial for maintaining gut barrier integrity, modulating immune responses, and regulating systemic metabolism. Finally, we summarize the multifaceted health effects of pectin-derived short-chain fatty acids (SCFAs) and propose that future efforts should focus on achieving a more comprehensive understanding of microbial and enzymatic mechanisms of pectin degradation, as well as complex cross-feeding networks, to inform the development of targeted nutritional interventions.
Source: Gut Microbes
Authors: Guiye Li, Chen Wang, Junying Bai
Institution: Southwest University
Language: English
Topic: Gut microbiota and health
Subfield: Molecular Biology
Domain: Life Sciences
SDG: Zero hunger
Open Access status: gold
Estimated APC paid: $3,060
Award: G8134668635
OpenAlex ID: W7203790275