Work

Discovery and Crystallographic Study of Water-Soluble Quaternary Ammonium-Based PD-1/PD-L1 Inhibitors with Anti-Angiogenic Activity

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6c01174

Authors: Jianwei Xu, Pan Yang, Xixiang Yang, Yaoyao Shu, Lirong Zhang, Jiayi Zhou, Ling Li, Yichang Ren, Zichao Yang, Yibei Xiao, Jianjun Chen

Institutions: Southern Medical University, China Pharmaceutical University, Sun Yat-sen University, Hubei University of Medicine

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Hubei Key Laboratory of Wudang Local Chinese Medicine Research, Science and Technology Program of Hubei Province

Awards: G1717693788, G2724485520, G442019508, G6902180368

OpenAlex ID: W7203819334

FWCI:

Cites: 80

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