Work

Reappraising obesity management in the GLP-1 receptor agonist era

Year: 2026

Type: article

Abstract: Incretin-based therapies are increasingly used for obesity management, raising debate about whether they could challenge or replace metabolic bariatric surgery (MBS). Here, we compare evidence for both treatments, focusing on effectiveness, limitations and costs. We also explore how obesity care pathways may evolve and highlight key evidence gaps that must be addressed to define the future roles of incretin-based therapies and MBS in obesity management.

Source: npj Metabolic Health and Disease

DOI: 10.1038/s44324-026-00126-0

Authors: T. Christmas, A. R. Ahmed, T. M-M. Tan

Institution: Imperial College London

Language: English

Topic: Bariatric Surgery and Outcomes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,590