Work

Fabrication of bilayer nerve conduits with sustained drug release using a multi-material, embedded 3D printing strategy

Year: 2026

Type: article

Abstract: NGF release and bioactivity assays. Finally, we demonstrated the fabrication of bilayer conduits with branched and multi-lumen geometries, which are challenging to fabricate with existing strategies. Altogether, these results highlight the promise of 3D printed nerve conduits leveraging tunable biomaterials to both physically guide and biochemically promote nerve regeneration.

Source: Journal of Materials Chemistry B

DOI: 10.1039/d6tb01916a

Authors: Betty Cai, Sadegh Ghorbani, Lili He, David Kilian, Wen-Chieh Chao, Jon-Paul Pepper, Sarah C. Heilshorn

Institutions: Stanford University, Technical University of Denmark, Stanford Medicine, Maastricht University

Language: English

Topic: 3D Printing in Biomedical Research

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Advanced Research Projects Agency for Health, National Science Foundation, National Institutes of Health, Natural Sciences and Engineering Research Council of Canada

Awards: 3D bioprinting of a bilayered, tissue engineered cornea, Novel, engineered bio-inks for 3D printing of complex, perfusable structures, Biomaterials for manufacturing of patient-derived organoids and assembloids, RECODE: Real-time analysis and environmental feedback for directed differentiation of liver organoids, G7988453276, G8155217980, An Engineered Bioprinting Platform to Study Neural Migration in Assembloids, Catheter-injectable, engineered biomaterial for sustained Neuregulin-1 delivery to the myocardium

OpenAlex ID: W7203867411

FWCI: 1.72

Cites: 67

Cited by: 1

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