Work

Mitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling

Year: 2026

Type: dataset

Abstract: Pparα AKO (adipose-scpecific knockout) mice, we obtained by crossing Pparαflox/flox mice (provided by F.J. Gonzales, described previously PMID: 28082284) and Adiponectin-Cre mice. All mice were housed, 5 per cage, in a temperature-controlled, specific pathogen–free facility with a 12-hour light /12-hour dark cycle and ad libitum access to water and food at room temperature (22±2°C). 12 weeks old male mice were sacrificed between ZT3-ZT4, and BAT was used for RNA sequencing (3 WT and 3 KO mice).

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.22017702

Authors: Midha, Mohit, Shen, Yachen, Karavaeva, Iuliia, Soccio, Raymond E., Lazar, Mitchell, Gerhart-Hines, Zachary

Institutions: University of Pennsylvania, University of Copenhagen, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Southern Denmark

Topic: Adipose Tissue and Metabolism

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7203892126

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