Work

YAP1-Driven PLCβ1 Impairs MHC-I Antigen Presentation and Limits Antitumor Immunity in Gastrointestinal Cancer

Year: 2026

Type: article

Source: Cancer Research

DOI: 10.1158/0008-5472.can-26-0635

Authors: Yingjing Zhang, Pengfei Su, Tian Yu, Bowen Hou, Jianpeng Gao, Fenglin Liu, Yakai Huang

Institutions: Shanghai Medical College of Fudan University, Fudan University, Fudan University Shanghai Cancer Center, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Beijing Tsinghua Chang Gung Hospital, Tsinghua University, Tongji Hospital, Huazhong University of Science and Technology

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Zhejiang Provincial Postdoctoral Science Foundation, National Natural Science Foundation of China

Awards: G7711295611, G8482028406

OpenAlex ID: W7203903588

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