First-of-its-kind 3D printed intravaginal ring for treatment of high-risk HPV (hrHPV) and early- stage cervical cancer
Year: 2026
Type: article
Abstract: My research focuses on developing a first-of-its-kind, 3D-printed intravaginal ring (IVR) designed to treat high-risk Human Papillomavirus (hr-HPV) and early-stage cervical cancer. Current invasive treatments can cause major complications and are often inaccessible to low-income populations. This self-administered ring is designed to continuously deliver targeted doses of Lopinavir and Ritonavir directly to the site over 30 days to eliminate precancerous cells without harming surrounding healthy tissue. Testing of both Lopinavir-only and combination rings has demonstrated a sustained, zero-order release of the treatments, supporting their potential as a safe, accessible treatment that only needs to be replaced once a month.
Source: UNC Libraries
DOI: 10.17615/08f5-am98
Author: Goodman, Madeleine
Institution: University of North Carolina at Chapel Hill
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7203907132
FWCI:
Cites:
Cited by:
Related to: